Myxedema Coma Diagnosis And Treatment Pdf
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Myxedema crisis is a severe life threatening form of decompensated hypothyroidism which is associated with a high mortality rate. Infections and discontinuation of thyroid supplements are the major precipitating factors while hypothermia may not play a major role in tropical countries. Low intracellular T3 leads to cardiogenic shock, respiratory depression, hypothermia and coma.
2015, Number 2
Myxedema coma: four patients diagnosed at the Internal Medicine Department of the Dr. Negrin University Hospital in Spain. Myxedema coma is a rare complication of hypothyroidism. Clinical examination may reveal hypotension, bradycardia, and hypothermia. Laboratory tests may show hyponatremia, lipid disorders, and elevations of creatine kinase, liver, and cardiac enzymes. We describe four cases diagnosed in our hospital during the period
Louis, and Assistant in Medicine, Washington University School of Medicine: A year-old white woman was admitted to Jewish Hospital with a two-day history of abdominal pain, vomiting of bilious material, and diarrhea. There was no previous history of weight gain, cold intolerance, or constipation. In the past few months she had had some drowsiness and a gradual decrease in mental acuity. The voice was deeply pitched and hoarse, the skin was dry, and the scalp hair was coarse. Rales were heard at the bases of both lungs. Examination of the abdomen revealed diffuse involuntary rigidity, rebound tenderness, and high-pitched, rushing bowel sounds. Deep tendon reflexes were abnormally delayed and symmetrical in response.
A forgotten but important risk factor for severe hyponatremia: myxedema coma. Email: benankasapoglu hotmail. Hypothyroidism is one of the most prevalent endocrine diseases. It can lead to a variety of clinical situations, including congestive heart failure, ileus, hypothermia, electrolyte disturbances and coma. A year-old male was admitted to the emergency department for confusion. He had had a cerebrovascular event five years ago and had been using anti-hypertensive medication since then. Systemic examination revealed coarse skin, hypoactive bowel sounds, decreased breath sounds and nonpitting pretibial edema.
This is a preview of subscription content, access via your institution. Rent this article via DeepDyve. Nicoloff JT. Thyroid storm and myxedema coma. Med Clin North Am ;— Google Scholar.
Download Citation | Myxedema coma: Diagnosis and treatment | Myxedema coma, the extreme manifestation of hypothyroidism, Request Full-text Paper PDF.
Myxedema coma is a rare clinical condition that represents severe hypothyroidism decompensation usually occurs in patient with long-standing undiagnosed hypothyroidism and is usually precipitated by infection and discontinuation of supplements treatment. Clinical symptoms are a mental decreased status, hypothermia, bradycardia, hypotension, hypoglycemia and hypoventilation. Thyroid hormone measurement allows the diagnosis. Protocols with rapid intravenous high doses of thyroid hormone, warming and mechanical ventilation may improve the prognosis. The purpose of the present article is to describe a fatal case of myxedema coma in elderly-woman occurring in the context of immunodeficiency.
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